lien? Subhuman primate? Deformed child? Mummified fetus? The Internet
is buzzing over the nature of "Ata," a bizarre 6-inch-long skeleton
featured in a new documentary on UFOs. A Stanford University scientist
who boldly entered the fray has now put to rest doubts about what
species Ata belongs to. But the mystery is not over.
The story began 10 years ago, when the diminutive remains were reportedly
found in a pouch in a ghost town in the Atacama Desert of Chile. Ata ended up in a private collection in Barcelona; producers of the film
Sirius latched onto the bizarre mummy as evidence of alien life.
Last fall, immunologist Garry Nolan, director of the National Heart,
Lung, and Blood Institute's Proteomics Center for Systems Immunology at
Stanford in California, heard about Ata from a friend and contacted the
filmmakers, offering to give them a scientific readout on the specimen.
They asked him to give it a shot.
Among the apparent abnormalities, Ata sports 10 ribs instead of the
usual 12 and a severely misshapen skull. "I asked our neonatal care unit
how you would go about analyzing it. Had they seen this kind of
syndrome before?" Nolan says. He was directed to pediatric radiologist
Ralph Lachman, co-director of the International Skeletal Dysplasia
Registry at Cedars-Sinai Medical Center in Los Angeles, California. "He
literally wrote the book on pediatric bone disorders," Nolan says.
Lachman was blown away, Nolan recalls: "He said, 'Wow, this is like
nothing I've ever seen before.' "
To study the specimen, Nolan sought clues in Ata's genome. He
initially presumed the specimen was tens or hundreds of thousands of
years old—the Atacama Desert may be the driest spot on the planet, so
Ata could have been preserved for eons. He consulted experts who had
extracted DNA from bones of the
Denisovans,
an Asian relative of European Stone Age Neandertals. It turned out that
their protocols weren't necessary. "The DNA was modern, abundant, and
high quality," he says, indicating that the specimen is probably a few
decades old.
To the chagrin of UFO hunters, Ata is decidedly of this world. After
mapping more than 500 million reads to a reference human genome,
equating to 17.7-fold coverage of the genome, Nolan concluded that Ata
"is human, there's no doubt about it." Moreover, the specimen's B2
haplotype—a category of mitochondrial DNA—reveals that its mother was
from the west coast of South America: Chile, that is.
Meanwhile, after examining x-rays, Lachman concluded that Aka's
skeletal development, based on the density of the epiphyseal plates of
the knees (growth plates at the end of long bones found only in
children), surprisingly appears to be equivalent to that of a 6- to
8-year-old child. If that holds up, there are two possibilities, Nolan
says. One, a long shot, is that Ata had a severe form of dwarfism, was
actually born as a tiny human, and lived until that calendar age. To
test that hypothesis, he will try to extract hemoglobin from the
specimen's bone marrow and compare the relative amounts of fetal versus
adult hemoglobin proteins. The second possibility is that Ata, the size
of a 22-week-old fetus, suffered from a severe form of a rare rapid
aging disease, progeria, and died in the womb or after premature birth.
Nolan hasn't yet turned up hits for genes known to be associated with
progeria or dwarfism. He's stepping up the search for mutations through
additional sequencing and casting a wider net. Another possibility is a
teratogen: a birth defect-inducing toxicant along the lines of
thalidomide. Nolan plans to analyze tissue using mass spectrometry to
look for toxicants or metabolites. But reports of a handful of other Tom
Thumb-sized skeletons from Russia and elsewhere have Nolan leaning
toward a genetic explanation.
At least one expert has a more prosaic take—but agrees that the
specimen is human. "This looks to me like a badly desiccated and
mummified human fetus or premature stillbirth," says William Jungers, a
paleoanthropologist and anatomist at Stony Brook University Medical
Center in New York. He notes that "barely ossified and immature
elements" of the hands and feet, and the wide open metopic suture, where
the two frontal bones of the skull come together down the middle of the
forehead. "Genetic anomalies are not evident, probably because there
aren't any," he says. Nolan responds that the rib number and epiphyseal
plate densities remain a riddle; while he is open to the fetus
hypothesis, he thinks that the jury is still out.
Nolan's analysis went viral this week; besieged as he has been by the
media circus, he doesn't regret having gotten involved in debunking a
claim of alien life. "I'm thrilled with the outcome," he says. Once the
analyses are complete, he says, he'll submit his findings for peer
review. The other claim Nolan debunks is that Ata is an elaborate hoax.
The x-rays clearly show these are real bones, complete with arterial
shadows, he says. "You just couldn't fake it," he says, adding, with a
laugh, "unless you were an alien."